What type of trait is sickle cell anemia?
Sickle cell disease is a hereditary disease seen most often among people of African ancestry. Caused by mutations in one of the genes that encode the hemoglobin protein, the disease is inherited as an autosomal recessive trait.
What trait causes sickle cell anemia?
Hemoglobin SS disease is the most common type of sickle cell disease. It occurs when you inherit copies of the hemoglobin S gene from both parents. This forms hemoglobin known as Hb SS. As the most severe form of SCD, individuals with this form also experience the worst symptoms at a higher rate.
Is sickle cell trait the same as sickle cell anemia?
Sickle cell trait is different from sickle cell disease, also known as sickle cell anemia. What is the difference between sickle cell trait and sickle cell disease? People with sickle cell trait carry only one copy of the altered hemoglobin gene and rarely have any clinical symptoms related to the disease.
What does it mean when you have sickle cell trait?
When someone has sickle cell trait (SCT), it means they have inherited one sickle cell gene and one normal gene. People with SCT have both normal red blood cells and some sickle shaped red blood cells. Most people with SCT do not have any symptoms of sickle cell disease.
What are the symptoms of sickle cell anemia?
Other symptoms include fatigue and difficulty in breathing. Sickle cell trait carriers can have one in every four children who will have sickle cell anemia in the future, or that is a 25 per cent chance. The other 25 per cent will have normal hemoglobin while the other 50 per cent can be carriers of the disease.
Can a person with sickle cell disease have red blood cells?
People with SCT have both normal red blood cells and some sickle-shaped red blood cells. Most people with SCT do not have any symptoms of sickle cell disease. As carriers of the sickle cell gene, though, parents have a 50% chance of passing the gene on to their children.
What are the different types of sickle cell disease?
Types of Sickle Cell 1 Sickle cell anemia (HbSS) Sickle cell anemia is the most common and severe type of SCD. 2 Sickle cell trait (HbAS) When someone inherits 1 gene for hemoglobin S and 1 gene for normal hemoglobin A, they have sickle cell trait. 3 HbSC. 4 HbS beta-thalassemia. 5 Other types of sickle cell disease. …
What are the signs of sickle cell trait?
Although most people show no signs or symptoms of the sickle cell trait, others may show some signs and symptoms which include: swollen, painful, and inflamed hands and feet, irregular heart beat, severe fatigue due to the lack of oxygen circulating throughout the body, headache, pallor, muscle weakness,…
How does a person get sickle cell anemia?
Sickle cell anemia is an inherited disease caused by a genetic mutation. A person who receives the defective gene from both their father and mother develops the disease; a person who receives one defective gene and a healthy one, will not have the disease but will be a carrier of the sickle cell trait.
What are the risk factors for sickle cell anemia?
Factors that influence the frequency of sickle cell anemia include geography, the prevalence of malaria, and the genetics of an individual’s parents and recent ancestors. Since this particular mutation is a genetically inherited disease, the primary factor affecting the frequency of sickle cell anemia is genetics.
Is the sickle cell anemia a dominant or recessive trait?
Dominant genetically: Sickle cell disease is inherited as an autosomal recessive condition, which is what you will read from online sources and textbooks. One must inherit the gene from both parents to have the disease. This assumes that inheriting one copy of the gene (trait patient) has no phenotype (medical problems).