Who is most affected by fragile X?

Who is most affected by fragile X?

Fragile X syndrome occurs more often in males and results in more severe disorder in males. Mutations in FMR1 are unusual when compared to mutations found in other genes. Some individuals carry between 55 – 200 CGG repeats called a “premutation,” usually without having symptoms associated with fragile X syndrome.

What do you need to know about fragile X syndrome?

Fragile X syndrome: Learning what families need, one person at a time. Fragile X syndrome (FXS) is a rare genetic disorder that has a major effect on a person’s life.

What is the life expectancy of a fragile X?

Life expectancy for people with fragile X syndrome is generally normal. Many affected people participate in an active lifestyle and have good health. While the life span of people with fragile X syndrome (FXS) is typically normal, there is very little information in the medical literature about adults with FXS.

How does fragile X affect speech and language?

Speech and language. Most boys with Fragile X have some problems with speech and language. They may have trouble speaking clearly, may stutter, or may leave out parts of words. They may also have problems understanding other people’s social cues, such as tone of voice or specific types of body language.

What causes the CGG triplet repeat in Fragile X?

Nearly all cases of fragile X syndrome are caused by an alteration (mutation) in the FMR1 gene where a DNA segment, known as the CGG triplet repeat, is expanded. Normally, this DNA segment is repeated from 5 to about 40 times.

What is the life expectancy of Fragile X syndrome?

Life expectancy for people with fragile X syndrome is generally normal. Many affected people participate in an active lifestyle and have good health.

What are some interesting facts about fragile X syndrome?

interesting Facts about fragile X syndrome. Fragile X syndrome is a hereditary disease caused due to a surge in mental retardation 1 (FMR1) gene from chromosome X. This gene is responsible for encoding a particular protein is required for the development of the brain.

What are the specific symptoms of Fragile X syndrome?

Fragile X Syndrome Symptoms. Though the severity of symptoms differs between men and women, some common fragile X syndrome symptoms are hyperactivity, impulsivity, anxiety, mood swings, tremors, and poor coordination.

What is the prognosis for Fragile X?

According to research, around 44% of women and 10% of men having fragile X syndrome are able to attain a high level of independence as adults. The life expectancy of a patient with fragile X syndrome is thought to be the same as any other normal person. The prognosis also depends on the degree of the symptoms of this condition.