Where did the disease cystic fibrosis come from?
(Magic mine/Shutterstock.com) Imagine the thrill of discovery when more than 10 years of research on the origin of a common genetic disease, cystic fibrosis (CF), results in tracing it to a group of distinct but mysterious Europeans who lived about 5,000 years ago.
Which is the most common mutation that causes cystic fibrosis?
The most common mutation that causes cystic fibrosis, a deadly genetic disease of the lungs and pancreas, is far more ancient than anybody suspected.
How does cystic fibrosis affect the digestive system?
Cystic fibrosis (CF) is a genetically inherited disease that causes persistent lung infections and makes it difficult to breathe. While primarily affecting the lungs, it can also impact the digestive system, including the pancreas, liver, intestines, and kidneys.
How often does cystic fibrosis occur in African Americans?
How common is cystic fibrosis? Cystic fibrosis is one of the most common genetic disorders in white people in the United States, occurring in one of every 3,200 live births. It is less common in African Americans (1 in 17,000), Asian Americans (1 in 31,000) and Native Americans.
Who are some famous people with cystic fibrosis?
Some famous people who have been impacted by Cystic Fibrosis include the following: Andrew Simmons, a professional wrestler who was diagnosed with Cystic Fibrosis. Bill Williams, a former professional soccer player. He played for Gillingham , Mansfield Town , Portsmouth , Queens Park Rangers and West Bromwich Albion .
Can you develop cystic fibrosis?
To develop cystic fibrosis, a person must inherit two cystic fibrosis genes. One gene is inherited from each parent. People who inherit only one cystic fibrosis gene are called cystic fibrosis carriers. They can pass the cystic fibrosis gene to their children. But they do not have the disease themselves.
What are the conditions of cystic fibrosis?
Cystic fibrosis (CF) is a lifelong condition that affects your lungs, digestive system, and other organs. Your mucus, tears, sweat, and saliva become so thick and sticky that they clog your lungs and digestive system. CF usually causes problems with breathing and with breaking down and absorbing food.
What is the karyotype of cystic fibrosis?
The cystic fibrosis karyotype is the same as every other karyotype. It is 46,XX for girls and 46,XY for boys. Cystic fibrosis is a single gene disease, where there is a mutation in both CFTR genes. Such a mutation will not show up in a karyotype, as it is too small to be noticeable when the chromosomes are condensed.