When was the first description of sickle cell disease?

When was the first description of sickle cell disease?

1910: First Description of Sickle Cell Disease. On the 15th of November 1910, Dr. James Herrick made the first official description in published literature of sickle cell disease.

Why are red blood cells shaped like sickle?

Haemoglobin is a substance in red blood cells, which carry oxygen around the body. Normal red blood cells are flexible and disc-shaped, but in sickle cell disease they can become rigid and shaped like a crescent or sickle because the haemoglobin inside them clumps together.

Why was Herrick interested in sickle cell disease?

Irons examined Noel’s blood under the microscope and saw red blood cells he described as “having the shape of a sickle”. When Herrick saw this in the chart, he became interested because he saw that this might be a new, unknown, disease.

Where are people with sickle cell disease from?

Other populations are also affected by sickle cell disease, including those from the Arabian Gulf, central India, Mediterranean area in northern Greece and southern Italy and eastern Turkey. In this period of time, there were more case reports of patients with sickle cell disease, strengthening the medical knowledge of the disease.

What is the origin of sickle cell?

Sickle cell was originated in Africa where malaria was killing a vast number of people ( Saladin , 2007). The sickle cell hemoglobin is not able to be digested by the parasites that cause malaria, making those with sickle cell resistant to malaria (Saladin, 2007).

How is everyday life with sickle cell disease?

Over a lifetime, sickle cell disease can harm a patient’s spleen, brain, eyes, lungs, liver, heart, kidneys, penis, joints, bones, or skin. A blood and bone marrow transplant is currently the only cure for sickle cell disease, and only a small number of people who have sickle disease are able to have the transplant.

Do you know how sickle cell started?

The sickle cell gene is passed from generation to generation in a pattern of inheritance called autosomal recessive inheritance. This means that both the mother and the father must pass on the defective form of the gene for a child to be affected.

How did the sickle cell disease get its name?

The disease gets its name because when you have SCD, your red blood cells look like a sickle, which is a C-shaped farm tool. Red blood cells contain a molecule called hemoglobin, which carries oxygen throughout the body. In a healthy person, hemoglobin is smooth, round, and flexible.