When should alendronate be stopped?

When should alendronate be stopped?

In a patient who has taken alendronate for five years and whose bone density is no longer in the osteoporotic range, discontinuing alendronate is a reasonable approach. The patient is likely to have substantial residual anti-resorptive activity during this period.

How many years can you take alendronic acid for?

Alendronic acid is generally prescribed long term, so you need to be happy it is the right option for you. To get the full benefits, alendronic acid should be taken regularly as instructed by your doctor or pharmacist. It is recommended that your treatment is formally reviewed by your doctor after five years.

Can alendronate be taken long term?

In studies of zoledronic acid use up to six years and alendronate use up to 10 years, continued treatment showed a reduction in both bone loss and vertebral fractures.

Can you take alendronate for more than 5 years?

These results suggest that for many women, discontinuation of alendronate for up to 5 years does not appear to significantly increase fracture risk. However, women at very high risk of clinical vertebral fractures may benefit by continuing beyond 5 years.

What happens if I stop taking alendronate?

Alendronate oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug suddenly or don’t take it at all: If you don’t take this drug, you may have a higher risk for bone breaks.

How long should a person take alendronate?

Answer From Ann Kearns, M.D., Ph. D. Bisphosphonates, the most common type of osteoporosis medications, are typically taken for at least 3 to 5 years. After that, your doctor will consider your risk factors in determining whether you should continue to take these or other osteoporosis medications.

What happens when you stop taking alendronate sodium?

Is hair loss a side effect of alendronate?

Less common side effects of alendronate include: Hair loss.

Is it OK to stop taking alendronate?

Take as directed Alendronate oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug suddenly or don’t take it at all: If you don’t take this drug, you may have a higher risk for bone breaks.

Should you take Fosamax for more than 5 years?

To reduce the risk of these rare complications, your doctor may recommend that you temporarily stop taking bisphosphonates after 3 to 5 years. This is sometimes called a bisphosphonate holiday. People who have severe osteoporosis may need to wait for 10 years before they stop taking these drugs.

How much alendronate is retained after 10 years?

Bone biologists have estimated that about 75 mg of alendronate is retained in the skeleton after 10 years of therapy with 10 mg a day or 70 mg a week dosing.3 Upon stopping treatment, the release of alendronate from remodeling is estimated to be approximately the same as taking a daily dose of 2.5 mg.

When to call your doctor after taking alendronate?

Call your doctor right away if you experience severe pain at any time during your treatment with alendronate. Your doctor may tell you to stop taking alendronate and your pain may go away after you stop taking the medication. talk to your doctor about other things you can do to prevent osteoporosis from developing or worsening.

What happens to BMD when you stop taking alendronate?

Those who were no longer taking alendronate showed a gradual rise in markers over five years. Their marker levels ended up close to the baseline measured 10 years earlier. This correlated with a slow decline in BMD after stopping alendronate.

How long can you take alendronate for osteoporosis?

Alendronate has been studied longer than any other osteoporosis medicine in a controlled clinical trials setting. The original dose ranging study was continued for a total of 10 years with about 200 women. Treatment with 10 mg of alendronate daily resulted in a continued gradual increase in BMD to an average of 14%.

Bone biologists have estimated that about 75 mg of alendronate is retained in the skeleton after 10 years of therapy with 10 mg a day or 70 mg a week dosing.3 Upon stopping treatment, the release of alendronate from remodeling is estimated to be approximately the same as taking a daily dose of 2.5 mg.

Call your doctor right away if you experience severe pain at any time during your treatment with alendronate. Your doctor may tell you to stop taking alendronate and your pain may go away after you stop taking the medication. talk to your doctor about other things you can do to prevent osteoporosis from developing or worsening.

Recent guidelines suggest that 4 years may be the magic number when it comes to alendronate. Four years of Alendronate has been shown to decrease the risk of hip and spine fractures without considerable risk of side effects that could lead to brittle bones.

Those who were no longer taking alendronate showed a gradual rise in markers over five years. Their marker levels ended up close to the baseline measured 10 years earlier. This correlated with a slow decline in BMD after stopping alendronate.