When does the course of atopic dermatitis begin?
Atopic dermatitis is characterized by severe pruritus, a chronically relapsing course, a distinctive distribution of eczematous skin lesions, and a personal or family history of atopic diseases. It often begins in early infancy and follows a course of remissions and exacerbations.
Why are T cells important for the pathogenesis of atopic dermatitis?
There is increasing evidence that T-cell responses to environmental or food allergens are important for the pathogenesis of atopic dermatitis. In patients with atopic dermatitis, the skin disease is most often associated with the existence of environmental or food allergen-specific IgE.
Which is the most common chronic skin disease of young children?
Atopic dermatitis is the most common chronic skin disease of young children, with a lifetime prevalence in US schoolchildren of up to 17%. Abnormal skin barrier differentiation and immune response genes play key roles in atopic dermatitis.
What kind of hypersensitivity is atopic dermatitis?
Atopic dermatitis (AD) is a hypersensitivity condition with familial clustering that involves skin and mucosal sites and is associated with respiratory conditions such as asthma and allergic rhinitis.
Why are the epidermis cells constantly undergoing mitosis?
The epidermis cells are constantly undergoing mitosis so that the outer dead cells containing keratin are rapidly replaced as they fall off, which occurs after so many days. Then the newer living cells start producing keratin, lose their cellular contents, and die, and the cycle goes on. The skin acts as a barrier to infection; therefore,…
Which is the following membrane lacks the epithelial layer?
______ is a chronic, and sometimes acute, relapsing skin disease that is caused by increased mitotic division of epidermal cells. Which of the following membranes lack an epithelial layer?
What is the correct name for a skin disorder?
____ is the type of epithelium that primarily functions in protection. _____ is the pigment in the skin that is primarily responsible for the colonization of the skin. _____ is the genetic inability to produce melanin. ____ is the correct name for a skin disorder that results in itching.
What kind of skin changes does chronic GVHD cause?
Patients with chronic GVHD exhibit skin changes that resemble either lichen planus or scleroderma, sometimes simultaneously or sequentially. Patients with chronic GVHD may have alopecia, nail dystrophy, and thickening of the skin (hyperkeratosis).