What percentage of the world has sickle cell disease?

Approximately 5% of the world’s population are healthy carriers of a gene for sickle-cell disease or thalassaemia. The percentage of people who are carriers of the gene is as high as 25% in some regions.

Where is sickle cell disease most common?

Sickle cell disease affects millions of people worldwide. It is most common among people whose ancestors come from Africa; Mediterranean countries such as Greece, Turkey, and Italy; the Arabian Peninsula; India; and Spanish-speaking regions in South America, Central America, and parts of the Caribbean.

Is Sickle cell disease increasing?

The number of sickle cell anemia cases is expected to increase about 30 percent globally by 2050, scientists said Tuesday in the journal PLOS Medicine. Countries in sub-Saharan Africa, where the disease is most common, will be the hardest hit.

How many people are affected by sickle cell disease?

It is estimated that: SCD affects approximately 100,000 Americans. SCD occurs among about 1 out of every 365 Black or African-American births. SCD occurs among about 1 out of every 16,300 Hispanic-American births.

Where is sickle cell disease most common in India?

India and Nepal. Sickle cell disease is common in ethnic groups of central India who share a genetic linkage with African communities, where the prevalence has ranged from 9.4 to 22.2% in endemic areas of Madhya Pradesh, Rajasthan and Chhattisgarh. It is also endemic among Tharu people of Nepal and India; however,…

Why is sickle cell anemia more common in Africa?

Sickle cell disease (SCD) is common throughout much of sub-Saharan Africa, affecting up to 3% of births in some parts of the continent. Nevertheless, it remains a low priority for many health ministries. The most common form of SCD is caused by homozygosity for the β-globin S gene mutation (SS disease).

Is there sickle cell anaemia in the United States?

In the United States, with no endemic malaria, the prevalence of sickle cell anaemia among people of African ancestry is lower (about 0.25%) than among people in West Africa (about 4.0%) and is falling.

What medical problems can be caused by sickle cell disease?

Sickle cell anemia can lead to a host of complications, including: Stroke. Sickle cells can block blood flow to an area of your brain. Acute chest syndrome. Pulmonary hypertension. Organ damage. Blindness. Leg ulcers. Gallstones. Priapism. Pregnancy complications.

What is the global prevalence of sickle cell disease (SCD)?

Background: Sickle cell disease (SCD) is a common haematological disorder, affecting millions of people worldwide. It is most prevalent in malarial endemic areas in the tropics where outcomes are often poor due to resource constraints, resulting in most children dying before reaching adulthood.

Does sickle cell disease affect a certain ethnic group?

Sickle cell disease is a genetic disorder that affects red blood cells in the body. The disease is found most often in African-Americans and Africans, but can also affect other ethnic groups.

Is sickle cell a contagious disease?

4. It’s Not Contagious. Sickle cell anemia is a disease, but it isn’t a contagious one. Parents may pass on this disease to their children or they may not. When both parents have the genetic trait that causes the sickle cells, then there is a 1 in 4 chance that a child will develop this disease.