What is the incidence rate of sickle cell anemia?
In the United States It is estimated that: SCD affects approximately 100,000 Americans. SCD occurs among about 1 out of every 365 Black or African-American births. SCD occurs among about 1 out of every 16,300 Hispanic-American births.
What percentage of Nigerians have sickle cell?
Nigeria has a population of 112 million with an annual growth rate of 3.2%. About 25% of adults throughout the country have the sickle cell trait, AS, while the Hb C trait is largely confined to the Yoruba people of southwestern Nigeria in whom it occurs in about 6%.
Which country has the highest rate of sickle cell disease?
Sickle Cell Disease (SCD), the most common blood disorder in the world, requires daily care and can cause major problems and long-term disability. Africa has the highest prevalence rates, with 20 – 30% in countries such as Nigeria, Cameroon, Republic of Congo, Gabon and Ghana.
Why is sickle cell prevalence in Africa?
It has been suggested that one factor associated with the high incidence of SCD in tropical Africa is the protection against Plasmodium malaria associated with having the SCT (Aygun & Odame, 2012).
How many people in Nigeria have sickle cell anaemia?
Frequencies of the carrier state determine the prevalence of sickle-cell anaemia at birth. For example, in Nigeria, by far the most populous country in the subregion, 24% of the population are carriers of the mutant gene and the prevalence of sickle-cell anaemia is about 20 per 1000 births.
Which is the country with the most sickle cell anemia?
Sickle cell anemia is predominant in tropical regions of sub-Saharan Africa where malaria is endemic. Nigeria records the highest disease incidence in the world with approximately 91,011 children born with the defect. The rate accounts for almost 2% of all newborns annually.
Why are sickle cell disease most common in Africa?
The occurrence of the disease is high in Africa due to the predominance of malaria. The disease is more dominant 10-40%, in equatorial countries of Africa and less 1-2%, in North Africa and less than 1% in South Africa.
When is World Sickle Cell Day in Nigeria?
Nigeria will join the global community to commemorate World Sickle Cell Day on June 19th – as designated by the United Nations; this is a day set […]
Frequencies of the carrier state determine the prevalence of sickle-cell anaemia at birth. For example, in Nigeria, by far the most populous country in the subregion, 24% of the population are carriers of the mutant gene and the prevalence of sickle-cell anaemia is about 20 per 1000 births.
What is the global prevalence of sickle cell disease?
What is the global prevalence of sickle cell disease (SCD)? Author: Joseph E Maakaron, MD; Chief Editor: Emmanuel C Besa, MD more… In several sections of Africa, the prevalence of sickle cell trait (heterozygosity) is as high as 30%.
Where does sickle cell anaemia occur in the world?
In broad terms, the prevalence of the sickle-cell trait (healthy carriers who have inherited the mutant gene from only one parent) ranges between 10% and 40% across equatorial Africa and decreases to between 1% and 2% on the north African coast and <1% in South Africa.
How many black babies are born with sickle cell disease?
SCD occurs among about 1 out of every 16,300 Hispanic-American births. About 1 in 13 Black or African-American babies is born with sickle cell trait (SCT).