What does it mean when a TB test is indeterminate?

An indeterminate result indicates an uncertain likelihood of M. tuberculosis infection. A borderline test result (T-Spot only) also indicates an uncertain likelihood of M. tuberculosis infection.

Why is Quantiferon gold indeterminate?

In addition to borderline results, Quantiferon tests may be uninterpretable if either the positive (mitogen) or negative control tubes fail to give an appropriate response. Such results are termed ‘indeterminate’ and the test may need to be repeated.

How long does it take for a Quantiferon gold test to come back?

How long does it take to get QFT results? This varies and depends on how frequently the laboratory in your area carries out the test. Results can be available in 24 hours. Unlike the TST, individuals do not need to return 2–3 days later in order to have the test read.

How do you read TB Gold test results?

How are QFT-Plus results interpreted?

1. Positive – suggests that TB infection is likely.
2. Negative – suggests that TB infection is unlikely.
3. Indeterminate – suggests the need for further investigations or repeat testing.

Is T spot the same as TB test?

T Cells Matter. 1 When your test looks for signs of TB infection using T cells, it matters how many T cells you include. The T-SPOT. TB test, unlike other tests, uses the same number each time.

What if my QuantiFERON TB Gold is positive?

You have a positive Tuberculin Skin Test (TST) or QuantiFERON blood test: what does this mean? If your TST (Mantoux) or Quantiferon blood test was found to be positive, this means you have a latent TB infection, but usually not the active disease.

What do you do if QuantiFERON gold is indeterminate?

tuberculosis infection who have an indeterminate QFT-G result, administration of a second test, either QFT-G or TST, might be prudent. The potential for TST to cause boosting and the need for two-step testing in settings conducting serial testing should be considered. For persons who are unlikely to have M.

What does TB Gold test positive mean?

A positive response to the QuantiFERON Tb Gold Test indicates towards the infection with the Mycobacterium tuberculosis. Although it does not mean that the person has active TB, rather it simply means that the person has been exposed to the mycobacterium tuberculosis bacterium.

Which is better QuantiFERON or T-spot?

TB and QuantiFERON-TB showed more positive test results than TST: 25.2 and 20.0% (P = 0.133) compared with 12.8% (P < 0.001 and P = 0.008, respectively). Agreement between T-SPOT.

Is the QuantiFERON TB Gold in tube test indeterminate?

Current Research in Tuberculosis, 3: 16-19. The QuantiFERON-TB Gold In-Tube Test was implemented as an aid for diagnosing tuberculosis infection or disease. The indeterminate results are uncommon but their importance cannot be neglected during diagnosis of tuberculosis infection.

What does an indeterminate TB test result mean?

An indeterminate result indicates an uncertain likelihood of M. tuberculosis infection. A borderline test result (T-Spot only) also indicates an uncertain likelihood of M. tuberculosis infection. A diagnosis of LTBI requires that TB disease be excluded by medical evaluation.

When did the QFT-G TB test come out?

The QuantiFERON®-TB Gold test (QFT-G) is a whole-blood test for use as an aid in diagnosing Mycobacterium tuberculosisinfection, including latent tuberculosis infection (LTBI) and tuberculosis (TB) disease. This test was approved by the U.S. Food and Drug Administration (FDA) in 2005.

What does a positive QFT-G mean for tuberculosis?

The QuantiFERON ®-TB Gold test (QFT A positive result suggests that M. tuberculosis infection is likely; a negative result suggests that infection is unlikely; and indeterminate result suggests QFT-G results cannot be interpreted as a result of low mitogen response or high background response.

Current Research in Tuberculosis, 3: 16-19. The QuantiFERON-TB Gold In-Tube Test was implemented as an aid for diagnosing tuberculosis infection or disease. The indeterminate results are uncommon but their importance cannot be neglected during diagnosis of tuberculosis infection.

An indeterminate result indicates an uncertain likelihood of M. tuberculosis infection. A borderline test result (T-Spot only) also indicates an uncertain likelihood of M. tuberculosis infection. A diagnosis of LTBI requires that TB disease be excluded by medical evaluation.

The QuantiFERON®-TB Gold test (QFT-G) is a whole-blood test for use as an aid in diagnosing Mycobacterium tuberculosisinfection, including latent tuberculosis infection (LTBI) and tuberculosis (TB) disease. This test was approved by the U.S. Food and Drug Administration (FDA) in 2005.

Are there false positives for qft4-tb gold plus?

(1) False-positive results may occur in patients with prior infection with Mycobacterium marinum, Mycobacterium szulgai, or Mycobacterium kansasii. No IFN-gamma response to M tuberculosis antigens was detected. Latent infection with M tuberculosis is unlikely. A single negative result does not exclude infection with M tuberculosis.