What causes high ALT AST and GGT?

What causes high ALT AST and GGT?

GGT is abundant in liver, kidney, pancreas and intestine. Increased AST: primary liver disease, acute myocardial infarction, muscle trauma and diseases, pancreatitis, intestinal surgery, burns, renal infarction, pulmonary embolism. Increased ALT: primary liver disease, biliary obstruction, pancreatitis.

Where are AST, ALT, ALP and GGT found?

ALT and AST are abundant liver enzymes. AST is also present in heart, muscle. ALP is present in nearly all tissues, primarily bone and liver. GGT is abundant in liver, kidney, pancreas and intestine.

What are Alt and AST and what do they mean?

ALT and AST are also known as aminotransferases or transaminases. They are considered good markers of liver inflammation that may impair its function.[9] ALT is regarded as a reliable marker of liver damage or liver disease, as well as an indicator of overall health.[7, 10-12] The name “liver function testing” is,…

Is the AST ALT ratio of alcohol reversible?

It can be reversible when treated with total alcohol abstinence. Alcoholic hepatitis and AST ALT are found together – the elevated ratio of these enzymes is highly indicative of this disease. Cirrhosis of the liver – the irreversible, final stage of liver damage.

What’s the normal ALT and AST for Mr Ta?

Mr TA, a healthy 45 year old business executive, is noted to have elevated ALT 85 IU/L and AST 90 IU/L (Normal: 0-45 IU/L). He has no symptom and is not jaundiced. He does not have any known past medical illness.

What’s the correlation between Alt, ALT, ALP and GGT?

GGT is abundant in liver, kidney, pancreas and intestine. Normal levels: ALT and AST normal ranges vary depending on lab, in general: ≤ 40 U/L. Mild ALT and AST elevations: (ALT and AST less than 5 times the upper limit of normal) –> Should be rechecked before extensive work-up is undertaken. Possible causes:

What does a high AST and ALT ratio mean?

However, it should be noted that most patients with high alcohol consumption but without severe liver disease often do not have an AST/ALT ratio above 1, which means that a high ratio could probably be a result of advanced alcoholic liver disease.

What are Alt and AST in an asymptomatic person?

The most common abnormalities of liver function test in an asymptomatic person is raised alanine aminotransferase (ALT) and raised aspartate aminotransferase (AST). The upper normal limit of ALT and AST varies from lab to lab, and is usually from 25 to 50 IU/L. 1 ALT and AST are produced by hepatocytes,…

Can a resistance exercise cause elevated GGT and Alt?

This was confirmed in another study which showed that resistance exercise can cause highly pathological liver function tests in healthy men; while ALT, AST and CK were greatly elevated, GGT was not. [16]