What causes disorders such as Klinefelter syndrome?
Klinefelter syndrome is caused by an additional X chromosome. This chromosome carries extra copies of genes, which interfere with the development of the testicles and mean they produce less testosterone (male sex hormone) than usual.
What is similar to Klinefelter syndrome?
These conditions include 48,XXXY syndrome, 48,XXYY syndrome, and 49,XXXXY syndrome. Like Klinefelter syndrome, these conditions affect male sexual development and can be associated with learning disabilities and problems with speech and language development.
Is Klinefelter syndrome a mental disorder?
Patients with Klinefelter syndrome have a higher burden of psychiatric conditions, especially depression, anxiety, schizophrenia and psychosis, than the general population. Adolescents are described as being sensitive, introspective and unassertive.
What age is Klinefelter syndrome diagnosed?
Klinefelter syndrome usually is not diagnosed until the time of puberty. At this point, the boy’s testicles fail to grow, and you may start to notice other symptoms.
What is the life expectancy of someone with Klinefelter syndrome?
According to research, Klinefelter syndrome can shorten your life expectancy up to two years. However, you can still live a long, full life with this condition.
What are the causes of Mosaic Klinefelter syndrome?
Klinefelter syndrome can be caused by: 1 One extra copy of the X chromosome in each cell (XXY), the most common cause 2 An extra X chromosome in some of the cells (mosaic Klinefelter syndrome), with fewer symptoms 3 More than one extra copy of the X chromosome, which is rare and results in a severe form
Is there such a thing as Klinefelter syndrome?
Males have an X and a Y (XY). But in rare cases, a male is born with an extra X chromosome (XXY). This is Klinefelter syndrome. It’s also called Klinefelter’s or XXY. Often, men don’t even know they have Klinefelter until they run into problems trying to have a child. There’s no cure, but it can be treated.
What causes the extra chromosome in Klinefelter’s syndrome?
As discussed earlier, Klinefelter’s syndrome arises due to an extra X chromosome. This extra chromosome arises from the accidental retention of a chromosome during a non-disjunction event during paternal and maternal Meiosis I (Gametogenesis).
Can a change in karyotype cause Klinefelter syndrome?
If there happens to be any alteration in the Karyotype can result in abnormal behaviour within the chromosomes and, therefore, causing Klinefelter syndrome. However, this syndrome is just one of the many other side effects of this change in Karyotype.
What causes Klinefelter syndrome in males and females?
Females have two X sex chromosomes (XX). Males have an X and a Y sex chromosome (XY). Klinefelter syndrome can be caused by: One extra copy of the X chromosome in each cell (XXY), the most common cause. An extra X chromosome in some of the cells (mosaic Klinefelter syndrome), with fewer symptoms.
What are the symptoms of Mosaic Klinefelter syndrome?
Causes. An extra X chromosome in some of the cells (mosaic Klinefelter syndrome), with fewer symptoms More than one extra copy of the X chromosome, which is rare and results in a severe form Extra copies of genes on the X chromosome can interfere with male sexual development and fertility.
Are there any other names for Klinefelter syndrome?
These conditions include 48,XXXY syndrome, 48,XXYY syndrome, and 49,XXXXY syndrome. Like Klinefelter syndrome, these conditions affect male sexual development and can be associated with learning disabilities and problems with speech and language development.
How is Klinefelter syndrome ( KS ) diagnosed and diagnosed?
Klinefelter syndrome. The condition is not typically inherited from one’s parents. The underlying mechanisms involves at least one extra X chromosome in addition to a Y chromosome such that the total chromosome number is 47 or more rather than the usual 46. KS is diagnosed by the genetic test known as a karyotype.