What are the characteristics of haemophilia?

What are the characteristics of haemophilia?

Unexplained and excessive bleeding from cuts or injuries, or after surgery or dental work. Many large or deep bruises. Unusual bleeding after vaccinations. Pain, swelling or tightness in your joints.

What is an example of hemophilia?

The two most common types of hemophilia are factor VIII deficiency (hemophilia A) and factor IX deficiency (hemophilia B, or Christmas disease). Hemophilia A and hemophilia B are inherited conditions and considered rare diseases by the National Institutes of Health.

How can hemophilia be diagnosed?

Diagnosis includes screening tests and clotting factor tests. Screening tests are blood tests that show if the blood is clotting properly. Clotting factor tests, also called factor assays, are required to diagnose a bleeding disorder. This blood test shows the type of hemophilia and the severity.

What is the main effect of hemophilia?

Hemophilia can result in: Bleeding within joints that can lead to chronic joint disease and pain. Bleeding in the head and sometimes in the brain which can cause long term problems, such as seizures and paralysis. Death can occur if the bleeding cannot be stopped or if it occurs in a vital organ such as the brain.

Why is it important to know about hemophilia?

Knowing the mutation that a person with hemophilia has is important for genetic testing of family members. It also can help predict how likely it is that a person will develop an inhibitor. Future treatments for people with hemophilia might work better for some types of mutations than for others.

What are the characteristics of hemophilia A patients?

Introduction: This research is conducted to describe the characteristic of Hemophilia A patients. Methods: Cross-sectional study conducted in 55 patients with Hemophilia A. The variables were age, bleeding episode, factor VIII level, and bleeding site. The data presented descriptively. Results: The largest group was 2-10 years old (52,73%).

Can a person with hemophilia have deep internal bleeding?

But some carriers can experience bleeding symptoms if their clotting factors are moderately decreased. The biggest risk factor for hemophilia is to have family members who also have the disorder. Complications of hemophilia may include: Deep internal bleeding. Bleeding that occurs in deep muscle can cause your limbs to swell.

What makes up the final blood clot in hemophilia?

Ultimately, fibrin is formed, the protein that crosslinks with itself to form a mesh that makes up the final blood clot. The protein involved with hemophilia A is factor VIII (factor 8) and with hemophilia B is factor IX (factor 9). Hemophilia A is caused by a mutation in the gene for factor VIII, so there is deficiency of this clotting factor.

What happens when a baby is born with hemophilia?

However, about one-third of the time, the baby with hemophilia is the first one in the family to be affected with a mutation in the gene for the clotting factor. Hemophilia can result in: Bleeding within joints that can lead to chronic joint disease and pain

What are the risk factors of hemophilia?

However, recent evidence suggests that hemophilia patients can suffer from atherosclerosis, or plaques in the arteries, at a similar rate as the general population. Furthermore, risk factors that contribute to cardiovascular disease, such as hypertension, or high blood pressure, are frequently present in men with severe hemophilia.

What are the effects of hemophilia?

Hemophilia mainly affects joints and muscles causing spontaneous bleeding after an injury or cut. Person with hemophilia can experience extended bleeding along with bruising leading to inflamed joints. Digestive problems and abdominal bleeding are the common concerns in people with hemophilia.

What are the forms of hemophilia?

The three forms of hemophilia are hemophilia A, B, and C. Hemophilia A is the most common type of hemophilia, and it’s caused by a deficiency in factor VIII. According to the National Heart, Lung, and Blood Institute ( NHLBI ), eight out of 10 people with hemophilia have hemophilia A. Hemophilia B ,…

What is the difference between hemophilia an and B?

Difference Between Hemophilia A and B Hemophilia B is less common than Hemophilia A. When consider the general population, Hemophilia B affects approximately one in 50,000 people while, Hemophilia A affects fewer than one in 10,000 people. Hemophilia A occurs due to the deficiency of factor VIII, whereas Hemophilia B occurs due to the deficiency of factor IX.