How does respiratory therapy help muscular dystrophy?

How does respiratory therapy help muscular dystrophy?

Effective airway clearance is critical for patients with DMD to prevent atelectasis and pneumonia. Ineffective airway clearance can hasten the onset of respiratory failure and death, whereas early intervention to improve airway clearance can prevent hospitalization and reduce the incidence of pneumonia (8).

Is respiratory muscle weakness restrictive?

Effect of the pattern of respiratory muscle weakness on lung volumes. It is well established that weakness of the respiratory muscles causes a restrictive ventilatory defect with a reduction in TLC.

What is the most common cause of respiratory muscle fatigue?

Increased work of breathing, mechanical disadvantage, neuromuscular disease, impaired nutritional status, shock, hypoxemia, acidosis, and deficiency of potassium, magnesium, and inorganic phosphorus are the major non-neurologic factors which contribute to respiratory muscle fatigue and failure.

Can muscular dystrophy cause shortness of breath?

In muscular dystrophy, progressive weakness of respiratory muscles can result in varying degrees of breathing difficulty. One of the most important respiratory muscles is the diaphragm, which sits just below the lungs and helps in the process of inhalation, or breathing in, which supplies oxygen to the lungs.

How are respiratory muscles affected by muscular dystrophy?

The impairment of respiratory muscles (that in muscular dystrophy become progressively weak and/or fatigued), combined with the high load against which the pump has developed its pressure, determine ventilatory failure.

What happens to the respiratory system with Duchenne muscular?

Loss of respiratory muscle strength, with ensuing ineffective cough and decreased ventilation, leads to pneumonia, atelectasis, and respiratory insufficiency in sleep and while awake (1). These complications are generally preventable with careful serial assessment of respiratory function.

How does respiratory health change as DMD progresses?

Respiratory Health as DMD progresses. Leg and heart muscles get much of the early attention in DMD, but as the disease progresses, the respiratory muscles also begin to weaken.

What causes ventilatory failure in muscular dystrophy?

Ventilatory failure in muscular dystrophy is caused by increased respiratory load and respiratory muscles weakness. Respiratory load increases in muscular dystrophy because scoliosis makes chest wall compliance decrease, atelectasis and fibrosis make lung compliance decrease, and airway obstruction makes airway resistance increase.

The impairment of respiratory muscles (that in muscular dystrophy become progressively weak and/or fatigued), combined with the high load against which the pump has developed its pressure, determine ventilatory failure.

Respiratory Health as DMD progresses. Leg and heart muscles get much of the early attention in DMD, but as the disease progresses, the respiratory muscles also begin to weaken.

Loss of respiratory muscle strength, with ensuing ineffective cough and decreased ventilation, leads to pneumonia, atelectasis, and respiratory insufficiency in sleep and while awake (1). These complications are generally preventable with careful serial assessment of respiratory function.

Ventilatory failure in muscular dystrophy is caused by increased respiratory load and respiratory muscles weakness. Respiratory load increases in muscular dystrophy because scoliosis makes chest wall compliance decrease, atelectasis and fibrosis make lung compliance decrease, and airway obstruction makes airway resistance increase.