Can you use Restasis eye drops more than twice a day?
You should use Restasis eye drops twice each day. You can use the drops any time of day, but try to keep your doses about 12 hours apart.
Can you use other eye drops with Restasis?

Restasis is an eye drop dosed in single-use vials used twice/day or as directed. Do not use other eye drops or medications during treatment with Restasis unless otherwise directed by your doctor.
How many drops are in a vial of Restasis?
Each vial contains 0.4 mL fill in a 0.9 mL LDPE vial; 30 or 60 vials are packaged in a polypropylene tray with an aluminum peelable lid. The entire contents of each tray (30 vials or 60 vials) must be dispensed intact.
How is Restasis used to treat dry eye?
Aqueous layer accounts for the majority of the tear film and hence lubricants helps in most of the dry eyes. Restasis will act by reducing the inflammation of the ocular surface caused by dry eye. It helps in retaining the tear film by repairing the ocular surface damage caused by dry eye.

How long does it take for Restasis to work?
Restasis will act by reducing the inflammation of the ocular surface caused by dry eye. It helps in retaining the tear film by repairing the ocular surface damage caused by dry eye. Hence it requires 4-6 weeks to show symptomatic improvement.
How often do you need to use the Restasis dropper?
The single use vials must be discard after one time dosing. I have been using the same restasis dropper morning and evening making its use four times for the past 9 years. The cost is $6000/year and I do not have any problems using it four times.
Is it dangerous to stop taking Restasis eye drops?
So far as I know, there are no dangers to stopping Restasis. The eye may get redder, since Res. is an anti-inflammatory. On the other hand, if you are allergic to Res., it may make your eye redder when you restart it. It is not dangerous to stop Restasis but you should check with your eye care provider.