Can phentermine cause heart valve problems?

Can phentermine cause heart valve problems?

Exposure to the anorectic drug fenfluramine, alone or in combination with phentermine, a noradrenergic central nervous system stimulant, has been associated with unusual cardiac valvular morphology and resultant regurgitation of the left- and right-sided heart valves.

What did phen phen do to the heart?

Fen and two migraine drugs, ergotamine and methysergide, which also are known to cause heart valve damage, were found to activate the serotonin receptor known as 5-HT2B located on heart’s valves (both the mitral and aortic).

Can valve disease be treated?

Treatment. Currently, no medicines can cure heart valve disease. However, lifestyle changes and medicines often can treat symptoms successfully and delay problems for many years. Eventually, though, you may need surgery to repair or replace a faulty heart valve.

How long can you live with valvular heart disease?

In developing countries, it progresses much more rapidly and may lead to symptoms in children less than 5 years of age. Around 80% of patients with mild symptoms live for at least 10 years after diagnosis.

Can phentermine hurt your heart?

Phentermine may cause a serious increase in your blood pressure. This may make your heart work harder. The extra stress on your heart may make your heart disease worse.

Can phentermine cause kidney damage?

Phentermine can cause elevation of the blood pressure and this can hasten the deterioration of kidney function.

What is the difference between phen phen and phentermine?

6) Is phentermine the same thing as fen-phen? Phentermine is one of the two medications in “fen-phen,” which is an off-label combination of fenfluramine and phentermine. Fenfluramine is another medication that activates the sympathetic nervous system like phentermine.

What are the side effects of Phen Phen?

Side Effects Dizziness, dry mouth, difficulty sleeping, irritability, nausea, vomiting, diarrhea, or constipation may occur. If these effects persist or worsen, notify your doctor or pharmacist promptly.

What are the effects of fen-phen on the heart?

From the WebMD Archives. Nov. 5, 2008 — Two banned obesity drugs may have lingering effects on the heart, according to a new study. The study shows that heart valve problems linked to the banned obesity drugs fenfluramine and/or dexfenfluramine typically last years after stopping those drugs.

Are there any heart valve problems from fenfluramine?

Study Shows Lingering Heart Valve Problems in Former Users of Banned Obesity Drugs Fenfluramine and Dexfenfluramine Nov. 5, 2008 — Two banned obesity drugs may have lingering effects on the heart, according to a new study.

What are the symptoms of fen-phen valve problems?

O’Neill says symptoms of valve problems may include severe bloating or swelling of the legs, or severe shortness of breath during exercise.

What’s the phen in the drug fen-phen?

The “phen” in fen-phen refers to a drug called phentermine, which wasn’t banned. The new study, published online today in BMC Medicine, shows what happened to the hearts of 5,743 former users of fenfluramine and/or dexfenfluramine.

From the WebMD Archives. Nov. 5, 2008 — Two banned obesity drugs may have lingering effects on the heart, according to a new study. The study shows that heart valve problems linked to the banned obesity drugs fenfluramine and/or dexfenfluramine typically last years after stopping those drugs.

O’Neill says symptoms of valve problems may include severe bloating or swelling of the legs, or severe shortness of breath during exercise.

Study Shows Lingering Heart Valve Problems in Former Users of Banned Obesity Drugs Fenfluramine and Dexfenfluramine Nov. 5, 2008 — Two banned obesity drugs may have lingering effects on the heart, according to a new study.

The “phen” in fen-phen refers to a drug called phentermine, which wasn’t banned. The new study, published online today in BMC Medicine, shows what happened to the hearts of 5,743 former users of fenfluramine and/or dexfenfluramine.