Can cyclosporine cause nerve damage?

Can cyclosporine cause nerve damage?

Cyclosporin A (CsA) induces neurological side effects in up to 40% of patients. A reversible posterior leukoencephalopathy syndrome is the most serious complication. Symptoms include headache, altered mental functioning, seizures, cortical blindness, and other visual disturbances, with hypertension.

Can cyclosporine cause muscle pain?

The following reactions occurred in 2% or less of cyclosporine-treated patients: allergic reactions, anemia, anorexia, confusion, conjunctivitis, edema, fever, brittle fingernails, gastritis, hearing loss, hiccups, hyperglycemia, migraine (Neoral®) muscle pain, peptic ulcer, thrombocytopenia, tinnitus.

Can cyclosporine cause leg swelling?

Check with your doctor right away if you have any of the following symptoms: blood in the urine, change in the frequency of urination or amount of urine, difficulty breathing, drowsiness, increased thirst, loss of appetite, nausea or vomiting, or swelling of the feet or lower legs, or weakness.

Does cyclosporine cause bone pain?

Severe bone pain as an adverse effect of cyclosporin therapy for Crohn’s disease.

What is cyclosporine side effects?

Common side effects of cyclosporine include:

  • High blood pressure.
  • Increased hair growth.
  • Swollen or inflamed gums.
  • Numbness or tingling of the hands or feet.
  • Other common side effects are tremors, restlessness, stomach upset, nausea, cramps, diarrhea, headache, and changes in blood sugar.

    Can you take cyclosporine long term?

    Generally speaking, patients can remain on cyclosporine indefinitely, as long as there is evidence that the drug is providing some benefit and there are no unwanted or adverse side effects.

    Are there any side effects from taking cyclosporine?

    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue pains in the stomach, side, or abdomen, possibly radiating to the back Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

    What kind of Medicine to take for cyclosporine?

    Applies to cyclosporine: oral capsule, oral capsule liquid filled, oral solution Only physicians experienced in management of systemic immunosuppressive therapy for the indicated disease should prescribe Sandimmune® ( cycloSPORINE) and Neoral® (cycloSPORINE, modified).

    What to do if you have pain in your leg?

    Pain may begin in your back and hip, then later extend down into your leg. Rest is often the cure for other pains of the leg, but not this one. It doesn’t help sciatica. Treatment may involve resting for a few days, along with taking anti-inflammatories and pain medications. Cold and heat can help with some symptoms.

    How does cyclosporine affect the risk of developing lymphoma?

    Increased susceptibility to infection and the possible development of lymphoma may result from immunosuppression. Hypertension and nephrotoxicity can occur at recommended dosages, and the risk increases with increasing dose and duration of cycloSPORINE therapy. Monitor blood levels and renal function to avoid toxicity.

    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue pains in the stomach, side, or abdomen, possibly radiating to the back Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

    What should I do if I miss a dose of cyclosporine?

    Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking cyclosporine?

    Pain may begin in your back and hip, then later extend down into your leg. Rest is often the cure for other pains of the leg, but not this one. It doesn’t help sciatica. Treatment may involve resting for a few days, along with taking anti-inflammatories and pain medications. Cold and heat can help with some symptoms.

    Why is cyclosporine used to treat kidney failure?

    This is because the immune system treats the new organ as an invader. Cyclosporine is used to prevent organ rejection after a kidney, heart, or liver transplant. Cyclosporine is also used to treat severe psoriasis or severe rheumatoid arthritis. Cyclosporine may also be used for purposes not listed in this medication guide.