Are there any GI manifestations of Down syndrome?
About 5% of patients with Down syndrome have GI manifestations, including duodenal atresia, Hirschsprung disease, and celiac disease. Many patients with trisomy 21 have otorhinolaryngologic manifestations, including hearing loss and recurrent ear infections.
When does cyclic vomiting syndrome start and end?
Episodes may make you feel very tired and drowsy. Each episode of cyclic vomiting syndrome tends to start at the same time of day, last the same length of time, and happen with the same symptoms and intensity as previous episodes. Episodes may begin at any time but often start during the early morning hours.
What causes cyclic vomiting syndrome ( NIDDK ) symptoms?
Triggers for an episode of cyclic vomiting may include: 1 emotional stress. 2 anxiety or panic attacks , especially in adults. 3 infections, such as colds, flu, or chronic sinusitis. 4 intense excitement before events such as birthdays, holidays, vacations, and school outings,… 5 lack of sleep. 6 (more items)
How does the extra chromosome 21 affect Down syndrome?
This chromosomal anomaly leads to both structural and functional defects in patients with Down syndrome. However, not all defects occur in each patient; there is a wide range of phenotypic variation. [ 1] The extra chromosome 21 affects almost every organ system and results in a wide spectrum of phenotypic consequences.
About 5% of patients with Down syndrome have GI manifestations, including duodenal atresia, Hirschsprung disease, and celiac disease. Many patients with trisomy 21 have otorhinolaryngologic manifestations, including hearing loss and recurrent ear infections.
How many Down syndrome patients have no symptoms?
About 13-14% of patients have radiographic evidence of atlantoaxial instability but no symptoms Only 1-2% of patients have symptoms that require treatment
How often do you vomit with cyclic vomiting syndrome?
You may vomit several times an hour. Episodes can last from a few hours to several days. Episodes may make you feel very tired and drowsy. Each episode of cyclic vomiting syndrome tends to start at the same time of day, last the same length of time, and happen with the same symptoms and intensity as previous episodes.