Are spindle cells always cancerous?
Spindle cell tumor is not a specific diagnosis or a specific type of cancer. The tumor may be a sarcoma, or it can be sarcomatoid — meaning another type of tumor (like a carcinoma) that looks like a sarcoma under the microscope.
What is the function of a spindle cell?
Spindle fibers form a protein structure that divides the genetic material in a cell. The spindle is necessary to equally divide the chromosomes in a parental cell into two daughter cells during both types of nuclear division: mitosis and meiosis. During mitosis, the spindle fibers are called the mitotic spindle.
What is the survival rate of spindle cell sarcoma?
Survival rates decreased with increasing age. The relative 5-year survival rates were 84% for those aged 20 to 49 years and 48% for those 50 to 69 years. Those older than 70 years had a 2-year relative survival rate of only 30%.
How is spindle cell carcinoma treated?
Spindle cell carcinoma (SCC) is a highly malignant pulmonary sarcomatoid carcinoma. There is no standard treatment for this disease, though chemotherapy, surgery and radiation therapy may be considered.
Where are spindle cells found in the body?
What are spindle cells? Spindle cells are specialized cells that are longer than they are wide. They are found both in normal, healthy tissue and in tumours. The most common type of normal spindle cell is called a fibroblast. Fibroblasts are support cells that are found in a type of connective tissue called stroma.
What kind of cancer is spindle cell carcinoma?
Spindle cell carcinoma is a type of cancer which usually originates in the connective tissues of the body. When cells from this type of cancer are viewed under a microscope, they appear spindle-shaped. It is a very aggressive form of cancer, and patients who are diagnosed generally do not live more than five years.
Can a spindle cell neoplasm be treated with surgery?
A spindle cell neoplasm is a rare growth found in connective tissue. It contains spindle-shaped cells that multiply abnormally and can become malignant. In the early stages of malignancy, it may be possible to treat the growth successfully with surgery to excise it.
Is the spindle cell lesions good or bad?
Spindle cell lesions: The Good, The Bad, and the Ugly Spindle cell lesions: The Good, The Bad, and the Ugly Leslie Turner, MD Objectives
What cells are spindle shaped?
See Article History. Fibroblast, the principal active cell of connective tissue. Fibroblasts are large, flat, elongated (spindle-shaped) cells possessing processes extending out from the ends of the cell body. The cell nucleus is flat and oval.
How long is spindle cell carcinoma life expectancy?
Unfortunately, since most cases of spindle cell sarcoma are not caught in the earliest stages, the overall survival rate is less than five years from the date of cancer detection. Since symptoms are often varied and can be confused with other things, this cancer is often not caught until it has spread.
What are the symptoms of spindle cell squamous cell carcinoma?
- Cutaneous SCC is asymptomatic and does not present any signs or symptoms (during the initial period)
- it is a slow-growing tumor
- it is not uncommon to find multiple tumors in an individual
- and nodules
- It may ulcerate and bleed.
What is spindle cell angiosarcoma caused from?
Spindle cell sarcoma can develop for a variety of reasons, including genetic predisposition but it also may be caused by a combination of other factors including injury and inflammation in patients that are already thought to be predisposed to such tumors. Spindle cells are a naturally occurring part of the body’s response to injury.